The two victims were rushed to an area hospital, where the female, later identified as Deborah Parker-Lykins, succumbed to her stabbing injuries, police said.
The man, whose identity has not been released pending autopsy results, died on Sept. 26.
A third person who was at the residence and is considered a witness to the attack was unharmed, police said.
Officers arrested Parker-Lykin’s son, 31-year-old Cody Parker, and charged him with her murder. He also faces a murder charge in connection with the second victim’s death.
A motive in the case has not been released.
The relationship between the suspect and the man is unclear.
Parker was treated for self-inflicted injuries and booked into the El Paso County jail.